HIV Research Today is a free monthly online journal that collates and summarizes the latest research about HIV, including details on human immunodeficiency virus, testing, treatment, prevention, vaccines, aids.

Volume 6 (2009), Issue 11 (November)

1. Human immunodeficiency virus type 1 (HIV-1) induces the cytoplasmic retention of heterogeneous nuclear ribonucleoprotein A1 by disrupting nuclear import: implications for HIV-1 gene expression.
   J Biol Chem, 284(45): 31350-62. [Abstract] [Full-text]
2. Induction of HIV-1 subtype B and AE-specific neutralizing antibodies in mice and macaques with DNA prime and recombinant gp140 protein boost regimens.
   Vaccine, 27(47): 6605-12. [Abstract] [Full-text]
3. The use of PEGylated poly [2-(N,N-dimethylamino) ethyl methacrylate] as a mucosal DNA delivery vector and the activation of innate immunity and improvement of HIV-1-specific immune responses.
   Biomaterials, 31(1): 115-23. [Abstract] [Full-text]
4. Small-molecule screening using a human primary cell model of HIV latency identifies compounds that reverse latency without cellular activation.
   J Clin Invest, 119(11): 3473-86. [Abstract] [Full-text]
5. Epigenetic activation of unintegrated HIV-1 genomes by gut-associated short chain fatty acids and its implications for HIV infection.
   Proc Natl Acad Sci U S A, 106(44): 18786-91. [Abstract] [Full-text]
6. Structure-function analysis of human immunodeficiency virus type 1 gp120 amino acid mutations associated with resistance to the CCR5 coreceptor antagonist vicriviroc.
   J Virol, 83(23): 12151-63. [Abstract] [Full-text]
7. Functional analysis and structural modeling of human APOBEC3G reveal the role of evolutionarily conserved elements in the inhibition of human immunodeficiency virus type 1 infection and Alu transposition.
   J Virol, 83(23): 12611-21. [Abstract] [Full-text]
8. Analysis of human immunodeficiency virus type 1 matrix binding to membranes and nucleic acids.
   J Virol, 83(23): 12196-203. [Abstract] [Full-text]
9. Mutations in the thumb allow human immunodeficiency virus type 1 reverse transcriptase to be cleaved by protease in virions.
   J Virol, 83(23): 12336-44. [Abstract] [Full-text]
10. Clade-specific evolution mediated by HLA-B*57/5801 in human immunodeficiency virus type 1 clade A1 p24.
    J Virol, 83(23): 12636-42. [Abstract] [Full-text]
11. The CDK inhibitor p21Cip1/WAF1 is induced by FcgammaR activation and restricts the replication of human immunodeficiency virus type 1 and related primate lentiviruses in human macrophages.
    J Virol, 83(23): 12253-65. [Abstract] [Full-text]
12. HIV-1 Nef dimerization is required for Nef-mediated receptor downregulation and viral replication.
    J Mol Biol, 394(2): 329-42. [Abstract] [Full-text]
13. Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy.
    Science, 326(5954): 818-23. [Abstract] [Full-text]
14. Detectable HIV viral load is associated with metabolic syndrome.
    J Acquir Immune Defic Syndr, 52(4): 459-64. [Abstract] [Full-text]
15. Plasma cytokine levels in Tanzanian HIV-1-infected adults and the effect of antiretroviral treatment.
    J Acquir Immune Defic Syndr, 52(4): 493-7. [Abstract] [Full-text]
16. Good neurocognitive performance measured by the international HIV dementia scale in early HIV-1 infection.
    J Acquir Immune Defic Syndr, 52(4): 488-92. [Abstract] [Full-text]
17. HIV-infected patients with a large thymus maintain higher CD4 counts in a 5-year follow-up study of patients treated with highly active antiretroviral therapy.
    Scand J Immunol, 70(6): 608-13. [Abstract] [Full-text]
18. Response to vicriviroc in treatment-experienced subjects, as determined by an enhanced-sensitivity coreceptor tropism assay: reanalysis of AIDS clinical trials group A5211.
    J Infect Dis, 200(11): 1724-8. [Abstract] [Full-text]
19. Clinical outcomes of elite controllers, viremic controllers, and long-term nonprogressors in the US Department of Defense HIV natural history study.
    J Infect Dis, 200(11): 1714-23. [Abstract] [Full-text]
20. Structural convergence between Cryo-EM and NMR reveals intersubunit interactions critical for HIV-1 capsid function.
    Cell, 139(4): 780-90. [Abstract] [Full-text]
21. Preferred sequences within a defined cleavage window specify DNA 3' end-directed cleavages by retroviral RNases H.
    J Biol Chem, 284(47): 32225-38. [Abstract] [Full-text]
22. Select resistance-associated mutations in blood are associated with lower CSF viral loads and better neuropsychological performance.
    Virology, 394(2): 243-8. [Abstract] [Full-text]
23. Visual DNA microarrays for simultaneous detection of human immunodeficiency virus type-1 and Treponema pallidum coupled with multiplex asymmetric polymerase chain reaction.
    Diagn Microbiol Infect Dis, 65(4): 372-8. [Abstract] [Full-text]
24. Neuromuscular diseases associated with HIV-1 infection.
    Muscle Nerve, 40(6): 1043-53. [Abstract] [Full-text]
25. Conserved HIV-1 epitopes continuously elicit subdominant cytotoxic T-lymphocyte responses.
    J Infect Dis, 200(12): 1825-33. [Abstract] [Full-text]
26. HIV-1 evolution following transmission to an HLA-B*5801-positive patient.
    J Infect Dis, 200(12): 1820-4. [Abstract] [Full-text]
27. HIV-1 Vif-mediated ubiquitination/degradation of APOBEC3G involves four critical lysine residues in its C-terminal domain.
    Proc Natl Acad Sci U S A, 106(46): 19539-44. [Abstract] [Full-text]
28. Human regulatory T cells are targets for human immunodeficiency Virus (HIV) infection, and their susceptibility differs depending on the HIV type 1 strain.
    J Virol, 83(24): 12925-33. [Abstract] [Full-text]
29. Effect of calcium-modulating cyclophilin ligand on human immunodeficiency virus type 1 particle release and cell surface expression of tetherin.
    J Virol, 83(24): 13032-6. [Abstract] [Full-text]
30. Quantifying differences in the tempo of human immunodeficiency virus type 1 subtype evolution.
    J Virol, 83(24): 12917-24. [Abstract] [Full-text]
31. Biaryl ethers as novel non-nucleoside reverse transcriptase inhibitors with improved potency against key mutant viruses.
    J Med Chem, 52(22): 7163-9. [Abstract] [Full-text]
32. The role of membranes in the organization of HIV-1 Gag p6 and Vpr: p6 shows high affinity for membrane bilayers which substantially increases the interaction between p6 and Vpr.
    J Med Chem, 52(22): 7157-62. [Abstract] [Full-text]
33. Azaindole hydroxamic acids are potent HIV-1 integrase inhibitors.
    J Med Chem, 52(22): 7211-9. [Abstract] [Full-text]
34. Impact of stimulatory pathways on adipogenesis and HIV-therapy associated lipoatrophy.
    Exp Biol Med (Maywood), 234(12): 1484-92. [Abstract] [Full-text]
35. Spermatozoa capture HIV-1 through heparan sulfate and efficiently transmit the virus to dendritic cells.
    J Exp Med, 206(12): 2717-33. [Abstract] [Full-text]
36. Incidence and risk factors of thrombocytopenia in patients receiving intermittent antiretroviral therapy: a substudy of the ANRS 106-window trial.
    J Acquir Immune Defic Syndr, 52(5): 531-7. [Abstract] [Full-text]
37. Factors that determine the efficiency of HIV-1 strand transfer initiated at a specific site.
    J Mol Biol, 394(4): 694-707. [Abstract] [Full-text]
38. Infection with different hiv subtypes is associated with CD4 activation-associated dysfunction and apoptosis.
    J Acquir Immune Defic Syndr, 52(5): 548-52. [Abstract] [Full-text]
39. Low-frequency K103N strengthens the impact of transmitted drug resistance on virologic responses to first-line efavirenz or nevirapine-based highly active antiretroviral therapy.
    J Acquir Immune Defic Syndr, 52(5): 569-73. [Abstract] [Full-text]
40. Germline-like predecessors of broadly neutralizing antibodies lack measurable binding to HIV-1 envelope glycoproteins: implications for evasion of immune responses and design of vaccine immunogens.
    Biochem Biophys Res Commun, 390(3): 404-9. [Abstract] [Full-text]
41. Influence of HIV infection on mortality in a cohort of patients treated for tuberculosis in the context of wide access to HAART, in Rio de Janeiro, Brazil.
    J Acquir Immune Defic Syndr, 52(5): 623-8. [Abstract] [Full-text]
42. Incidence of HIV-1, syphilis, hepatitis B, and hepatitis C virus infections and predictors associated with retention in a 12-month follow-up study among men who have sex with men in Beijing, China.
    J Acquir Immune Defic Syndr, 52(5): 604-10. [Abstract] [Full-text]
43. Differential survival benefit of universal HAART access in Brazil: a nation-wide comparison of injecting drug users versus men who have sex with men.
    J Acquir Immune Defic Syndr, 52(5): 629-35. [Abstract] [Full-text]
44. Increased risk of genital ulcer disease in women during the first month after initiating antiretroviral therapy.
    J Acquir Immune Defic Syndr, 52(5): 600-3. [Abstract] [Full-text]
45. Evaluating adherence to medication in children and adolescents with HIV.
    Arch Dis Child, 94(12): 970-3. [Abstract] [Full-text]
46. A prospective study of risk factors for herpes simplex virus type 2 acquisition among high-risk HIV-1 seronegative women in Kenya.
    Sex Transm Infect, 85(7): 489-92. [Abstract] [Full-text]
47. Neurologic presentations of AIDS.
    Neurol Clin, 28(1): 253-75. [Abstract] [Full-text]
48. Quantifying the relationship between HIV-1 susceptibility to CCR5 antagonists and virus affinity for antagonist-occupied co-receptor.
    Virology, 395(2): 268-79. [Abstract] [Full-text]
49. Lactic acidosis in HIV-exposed infants with perinatal exposure to antiretroviral therapy.
    Ann Trop Paediatr, 29(4): 257-61. [Abstract] [Full-text]
50. Dopaminergic neurotoxicity of HIV-1 gp120: reactive oxygen species as signaling intermediates.
    Brain Res, 1306: 116-30. [Abstract] [Full-text]
51. Inhibition of the dimerization and active site of HIV-1 protease by secondary metabolites from the Vietnamese mushroom Ganoderma colossum.
    J Nat Prod, 72(11): 2019-23. [Abstract] [Full-text]
52. A recombination hot spot in HIV-1 contains guanosine runs that can form a G-quartet structure and promote strand transfer in vitro.
    J Biol Chem, 284(49): 33883-93. [Abstract] [Full-text]

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