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Immunologic and clinical responses to highly active antiretroviral therapy in patients with HIV infection aged >50 years.

Cuzin L, Delpierre C, Gerard S, Massip P, Marchou B

Department of Infectious and Tropical Diseases, Hopital Purpan, Toulouse, France. cuzin.l@chu-toulouse.fr

We analyzed the effect of age on highly active antiretroviral therapy efficacy and tolerance in 639 patients with human immunodeficiency virus (HIV) infection (99 of whom were aged >50 years, and 540 of whom were aged <50 years). Late testing, which was more frequent in the older age group, was the only independent factor associated with immunologic and clinical evolution of infection. Age >50 years was associated with earlier treatment discontinuation.

Published 8 August 2007 in Clin Infect Dis, 45(5): 654-7.
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