HIV Research Today is a free monthly online journal that collates and summarizes the latest research about HIV, including details on human immunodeficiency virus, testing, treatment, prevention, vaccines, aids.

The silent defense: micro-RNA directed defense against HIV-1 replication.

Kumar A

Department of Biochemistry & Molecular Biology, George Washington University, Washington, DC, USA. akumar@gwu.edu

MicroRNAs play critical role in regulating gene expression. MicroRNA profile of particular cell type bears the signature of cell type specific gene expression. Given that viral pathogens replicate by evading host defenses, research is now focused on the miRNA-regulated genes that critically regulate HIV-1 propagation in human host cells.

Published 7 May 2007 in Retrovirology, 4: 26.
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