HIV Research Today is a free monthly online journal that collates and summarizes the latest research about HIV, including details on human immunodeficiency virus, testing, treatment, prevention, vaccines, aids.

Immune responses and HIV: a little order from the chaos.

O'Connor DH, Burton DR

University of Wisconsin-Madison, Department of Pathology and Laboratory Medicine, Madison, WI 53711, USA. doconnor@primate.wisc.edu

HIV is evolution gone mad and bad. The virus infects a person and rapidly diversifies to become a huge swarm of viruses, each equipped differently to resist the onslaught of diverse T cells and antibodies. We can't expect to predict details of the struggle between virus and immunity, right? Wrong--maybe we can make some predictions, say two new landmark studies with potentially huge consequences for AIDS vaccine design.

Published 21 March 2006 in J Exp Med, 203(3): 501-3.
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