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Performance of a rapid immunochromatographic screening test for detection of antibodies to human immunodeficiency virus type 1 (HIV-1) and HIV-2: experience at a tertiary care hospital in South India.

Vijayakumar TS, David S, Selvaraj K, Viswanathan T, Kannangai R, Sridharan G

Department of Clinical Virology, Christian Medical College, Vellore, Tamil Nadu PIN 632004, India.

The performance characteristics of a rapid immunochromatographic-screening test, SD Bioline HIV-1/2 3.0 (Standard Diagnostics Inc., Kyonggi-do, South Korea) on 23,754 sera and 30 plasma samples are reported. The sensitivity and specificity for the assay on serum samples are 100% and 99.4%, respectively. The assay detected antibodies in individuals infected with human immunodeficiency virus type 1 (HIV-1) genotypes A and C and HIV-2. This straightforward assay is a reliable diagnostic tool for screening HIV in resource-poor settings.

Published 5 August 2005 in J Clin Microbiol, 43(8): 4194-6.
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