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HIV Research Today is a free monthly online journal that collates and summarizes the latest research about HIV, including details on human immunodeficiency virus, testing, treatment, prevention, vaccines, aids.


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Safety and immunogenicity of 4 intramuscular double doses and 4 intradermal low doses vs standard hepatitis B vaccine regimen in adults with HIV-1: a randomized controlled trial.

Launay O, van der Vliet D, Rosenberg AR, Michel ML, Piroth L, Rey D, Colin de Verdière N, Slama L, Martin K, Lortholary O, Carrat F,

Paris Descartes University, France. odile.launay@cch.aphp.fr

Published 13 April 2011 in JAMA, 305(14): 1432-40.
Full-text of this article is available online (may require subscription).


Articles on HIV published 13 April 2011:

Safety and immunogenicity of 4 intramuscular double doses and 4 intradermal low doses vs standard hepatitis B vaccine regimen in adults with HIV-1: a randomized controlled trial.   JAMA, 305(14): 1432-40.

[Abstract] [Full-text]


Articles on HIV published 6 April 2011:

Low-frequency HIV-1 drug resistance mutations and risk of NNRTI-based antiretroviral treatment failure: a systematic review and pooled analysis.   JAMA, 305(13): 1327-35.

[Abstract] [Full-text]

Low-frequency HIV-1 drug resistance mutations and risk of NNRTI-based antiretroviral treatment failure: a systematic review and pooled analysis.   JAMA, 305(13): 1327-35.

[Abstract] [Full-text]

Low-frequency HIV-1 drug resistance mutations and risk of NNRTI-based antiretroviral treatment failure: a systematic review and pooled analysis.   JAMA, 305(13): 1327-35.

[Abstract] [Full-text]


Articles on HIV published 14 March 2011:

Pol as a target for antibody dependent cellular cytotoxicity responses in HIV-1 infection.   Virology, 412(1): 110-6.

Antibody-dependent cellular cytotoxicity (ADCC) may assist in preventing HIV or delaying disease progression. Most prior studies have analysed Env-specific ADCC responses. We hypothesized that effective ADCC-based immunity may target conserved internal viral proteins such as Pol. We analysed the ability overlapping Pol peptides to induce activation of NK cells via ADCC. We prospectively studied ADCC responses in 83 HIV+ subjects followed for 3 years. Pol peptides were commonly targeted by ADCC ... [Abstract] [Full-text]


Articles on HIV published 1 March 2011:

Association between medication possession ratio, virologic failure and drug resistance in HIV-1-infected adults on antiretroviral therapy in Côte d'Ivoire.   J Acquir Immune Defic Syndr, 56(4): 356-64.

[Abstract] [Full-text]

Association between medication possession ratio, virologic failure and drug resistance in HIV-1-infected adults on antiretroviral therapy in Côte d'Ivoire.   J Acquir Immune Defic Syndr, 56(4): 356-64.

[Abstract] [Full-text]


Articles on HIV published 25 February 2011:

DCs and NK cells: critical effectors in the immune response to HIV-1.   Nat Rev Immunol, 11(3): 176-86.

Dendritic cells (DCs) and natural killer (NK) cells have central roles in antiviral immunity by shaping the quality of the adaptive immune response to viruses and by mediating direct antiviral activity. HIV-1 infection is characterized by a severe dysregulation of the antiviral immune response that starts during early infection. This Review describes recent insights into how HIV-1 infection affects DC and NK cell function, and the roles of these innate immune cells in HIV-1 pathogenesis. The ... [Abstract] [Full-text]


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